The study want to prove that cocaine is yet another polluter thar alters the fish behaviour even in the small quantities that can be found in the wild in polluted areas. Not that something is special or different about cocaine pollution.
So the control group in this case are fishes with an implant with no drug at all.
https://www.cell.com/current-biology/fulltext/S0960-9822(26)...
BTW, did you knew municipalities can easily measure fluctuations in drug usage by testing the sewage water? In fact, sometimes they can see clear differences between different parts of the city.
Save the fish.
The Pope of the time loved the stuff and awarded the company a Vatican medal for it.
Fish lack urea cycle, so they produce and excrete significant amounts of ammonia as part of normal metabolism.
Yep. Not just drugs are monitored this way, but also the spread of infectious diseases. That can lead to sometimes pretty weird findings - for example, polio virus is supposed to be extinct, but every so often it shows up in sewage monitoring of major German cities [1]. The cause most likely are people (tourists and immigrants) from Africa and Asia that got an attenuated virus-based vaccination in their home country shortly before they came here.
Covid is, at least in Bavaria, also part of the regular monitoring schedule [2], Austria monitors for Covid, RSV and influenza [3].
[1] https://www.aerzteblatt.de/news/erreger-der-kinderlaehmung-i...
I expect the fish to be more active. A coffee patch would be a nice 4th group as another control.
[1] Chewing the leaves of coke is common in many countries of South America, https://en.wikipedia.org/wiki/Acullico
https://wastewater-observatory.jrc.ec.europa.eu/#/content/th...
Also, Wastewater analysis and drugs — a European multi-city study:
https://www.euda.europa.eu/publications/pods/waste-water-ana...
[0] https://web.archive.org/web/20210327150247/https://arachnidl...
If roaming more widely introduces them to more productive food opportunities (or, lower predation) than their closer ecology, then it would be beneficial for them. If it does not, then it wouldn't be. Neither context is determined in the basic finding that cocaine causes them to roam more widely.