Data availability

The datasets generated and analysed during the current study are available from the corresponding authors upon request.

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Acknowledgements

We thank D.-H. Lee, X. Lin, Y. Qi, J. Wang and C. Tang for helpful discussions. We also thank H. Eisaki, G. D. Gu, A. Haug, Z. Zhang, J. Shao and Y. Zhao for their help with the experiment. Part of the sample fabrication was conducted at Nano-fabrication Laboratory at Fudan University.

Funding

H.L., Y.Y., L.M., W.R. and Y.Z. acknowledge support from National Key R&D Program of China (grant number 2022YFA1403301), Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (grant number JYB2025XDXM120), National Science Foundation of China (grant number 12350404), Quantum Science and Technology-National Science and Technology Major Project (grant number 2024ZD0300104), and Shanghai Municipal Science and Technology Commission (grant numbers 23JC1400600 and 2019SHZDZX01). W.R. acknowledges additional support from National Science Foundation of China (grant number 12274087) Shanghai Science and Technology Development Funds (grant number 22QA1400600). Y.Y. acknowledges addtional support from Shanghai Municipal Science and Technology Project (grant number 25DZ3008100). D. Song acknowledges support from the Max Planck-UBC-UTokyo Centre for Quantum Materials and the Canada First Research Excellence Fund, Quantum Materials and Future Technologies. P.C. acknowledges support from National Key R&D Program of China (grant number 2022YFA1403102), Quantum Science and Technology-National Science and Technology Major Project (grant number 2021ZD0302502), National Science Foundation of China (grant number 12074424), the Fundamental Research Funds for the Central Universities, and the Research Funds of Renmin University of China. Y.C, L.Z. and X.Z. acknowledge support from National Science Foundation of China (grant number 11888101). Z.W. acknowledges support from National Science Foundation of China (grant number 12347107) and National Key R&D Program of China (grant number 2021YFA1402101). X.H.C. acknowledges support from the National Science Foundation of China (grant numbers 11888101 and 11534010), the National Key R&D Program of China (grant numbers 2017YFA0303001 and 2016YFA0300201), Strategic Priority Research Program of the Chinese Academy of Sciences (grant number XDB25000000) and the Key Research Program of Frontier Sciences, CAS (grant number QYZDY-SSW-SLH021). This work has been supported by the New Cornerstone Science Foundation.

Author information

Authors and Affiliations

1. State Key Laboratory of Surface Physics and Department of Physics, Fudan University, Shanghai, China

   Hengsheng Luo, Yijun Yu, Liguo Ma, Peng Cai, Jian Shen, Wei Ruan & Yuanbo Zhang

2. Institute for Nanoelectronic Devices and Quantum Computing, Fudan University, Shanghai, China

   Hengsheng Luo, Jian Shen, Wei Ruan & Yuanbo Zhang

3. Shanghai Branch, Hefei National Laboratory, Shanghai, China

   Hengsheng Luo, Jian Shen, Wei Ruan & Yuanbo Zhang

4. Shanghai Research Center for Quantum Sciences, Shanghai, China

   Hengsheng Luo, Jian Shen, Wei Ruan & Yuanbo Zhang

5. Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, China

   Hengsheng Luo, Jian Shen, Wei Ruan & Yuanbo Zhang

6. Stewart Blusson Quantum Matter Institute, University of British Columbia, Vancouver, British Columbia, Canada

   Dongjoon Song

7. Zhejiang Key Laboratory of Micro-nano Quantum Chips and Quantum Control, and School of Physics, Zhejiang University, Hangzhou, China

   Liguo Ma

8. School of Physics and Key Laboratory of Quantum State Construction and Manipulation (Ministry of Education), Renmin University of China, Beijing, China

   Peng Cai

9. Tsung-Dao Lee Institute & School of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China

   Ruidan Zhong

10. National Laboratory for Superconductivity, Beijing National undefinedoratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China

Yiwen Chen, Lin Zhao & Xingjiang Zhou

11. Department of Condensed Matter Physics, The Weizmann Institute of Science, Rehovot, Israel

Dan Shahar

12. Institute for Advanced Study and Collaborative Innovation Center of Quantum Matter, Tsinghua University, Beijing, China

Zhengyu Weng

13. Key Laboratory of Strongly Coupled Quantum Matter Physics, Chinese Academy of Sciences, and Department of Physics, University of Science and Technology of China, Hefei, China

Xian Hui Chen

14. New Cornerstone Science Laboratory, Fudan University, Shanghai, China

Yuanbo Zhang

Authors

1. Hengsheng Luo
2. Dongjoon Song
3. Yijun Yu
4. Liguo Ma
5. Peng Cai
6. Ruidan Zhong
7. Yiwen Chen
8. Lin Zhao
9. Jian Shen
10. Dan Shahar
11. Xingjiang Zhou
12. Zhengyu Weng
13. Xian Hui Chen
14. Wei Ruan
15. Yuanbo Zhang

Contributions

Y.Z., W.R., X.H.C. and J.S. supervised the project. D. Song, R.Z., Y.C., L.Z. and X.Z. synthesized the bulk crystals. H.L., L.M. and P.C. fabricated STM devices and performed STM measurements. H.L. and Y.Y. fabricated transport devices. H.L. performed transport measurement. D. Shahar provided InO_x_ thin films. H.L., Y.Y., Z.W., W.R. and Y.Z. analysed the data and wrote the paper with input from all authors.

Corresponding authors

Correspondence to Xian Hui Chen, Wei Ruan or Yuanbo Zhang.

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Nature thanks Jianfeng Ge, Nicola Poccia and Boris Spivak for their contribution to the peer review of this work.

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Luo, H., Song, D., Yu, Y. et al. Superconducting 2D cuprate with a single CuO2 plane. Nature (2026). https://doi.org/10.1038/s41586-026-10857-1

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• Received: 18 October 2024

• Accepted: 26 June 2026

• Published: 12 August 2026

• Version of record: 12 August 2026

• DOI: https://doi.org/10.1038/s41586-026-10857-1